Depression: Taking Antidepressants Safely

Overview

If your doctor has prescribed antidepressants, there are some important things to know about how to take them. Following these guidelines can reduce problems and help you get the most benefit from your medicine.

Antidepressants work best when you take them exactly as your doctor prescribed them. This also helps reduce side effects.
You may start to feel better within 1 to 3 weeks after you start taking this medicine. But it can take as long as 6 to 8 weeks to see improvement. If you don't start to feel better by 3 weeks, talk to your doctor.
Antidepressants can cause side effects. But most of them are mild and go away after you take the medicine for a few weeks.
It's best to take these medicines for at least 6 months after you start to feel better. This can help keep you from feeling depressed again (relapse).
Be sure your doctor knows about any other health problems you have and any medicines you take. These things can affect which medicine your doctor prescribes for you.
Quitting antidepressants too quickly can cause withdrawal symptomswithdrawal symptoms or cause depression to come back. If you have a problem with your medicine or are ready to quit taking it, work with your doctor to slowly reduce the dose over time.

How to take antidepressant medicine wisely

If your doctor has prescribed antidepressants, try these tips. They can help you get the most from your medicine.

Share your health history with your doctor.
Tell your doctor about your other medicines and health conditions. These things can affect which antidepressant your doctor prescribes for you. Tell your doctor if you or anyone in your family has had bipolar disorder or used antidepressants before.
Take your medicine as prescribed.
It works best and has fewer side effects when you take it exactly as your doctor prescribed. If you miss a dose and it's not too late in the day, you can still take it. Don't double up doses.
Keep taking your medicine for a while.
If antidepressants work well for you, your doctor may suggest taking them for at least 6 months after you feel better. This may help keep you from getting depressed again.
Let your doctor know if your symptoms aren't getting better.
You may need a different dose. Or you may need to try several different medicines. It can take a while to find the medicine and dosage that work best.
Don't take any new medicines unless you talk to your doctor first.
Even common medicines like aspirin and some vitamins and herbs can cause problems if you use them while you take antidepressants.
Do not drink alcohol.
It can make the side effects worse.
Don't stop taking your medicine on your own.
Quitting antidepressants too quickly can cause withdrawal symptoms. It can also cause depression to come back. If you are having a problem with your medicine or are ready to quit taking it, work with your doctor. They can help you to slowly reduce the dose over a span of a few weeks.
Call your doctor right away for serious side effects.
Watch for:
- Warning signs of suicide. These include talking or writing about death, giving away belongings, and withdrawing from family and friends.
- Manic behaviorManic behavior. This includes having very high energy, sleeping less than normal, being impulsive, or being grouchy or restless.
- Serotonin syndrome. This can happen if you take too much antidepressant medicine or take more than one type of medicine that affects serotonin. Signs may include high body temperature, clumsiness, nausea, and feeling restless.

Current as of: July 31, 2024

Author: Ignite Healthwise, LLC StaffIgnite Healthwise, LLC Staff

Clinical Review BoardClinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of UseTerms of Use. Learn how we develop our contenthow we develop our content.

To learn more about Ignite Healthwise, LLC, visit webmdignite.comwebmdignite.com.

Page Footer

I want to...

Audiences

Secure Member Sites

The Cigna Group Information

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., Cigna HealthCare of Georgia, Inc., Cigna HealthCare of North Carolina, Inc., Cigna HealthCare of South Carolina, Inc., and Cigna HealthCare of Texas, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities a listing of the legal entities that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details Details