Apomorphine Sublingual Film (APOMORPHINE FILM - SUBLINGUAL)

Instructions

Do not use if the pouch containing the medicine is torn or damaged.

Remove medicine from the foil just before using. Place the sheet under your tongue and let it dissolve completely.

Only use 1 sheet at a time.

Do not cut the sheet.

Drink some water to moisten your mouth before using the medicine.

Do not chew or swallow it whole.

Do not talk, swallow, chew, or move the medicine after placing it under your tongue.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

If you need to take a second dose, wait at least 2 hours after taking your first dose.

Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor and pharmacist about all your medicines. Include prescription and over-the-counter medicines, vitamins, and herbal medicines.

Tell your doctor if symptoms do not get better or if they get worse.

Your doctor may prescribe other medications to reduce side effects. Follow instructions carefully.

Do not take the medicine more than five times during 24 hours.

Cautions

This medicine can be habit-forming. If you use this medicine regularly for a long time, it can lead to withdrawal symptoms when you stop. Please use this medicine only as directed.

If you stop this medicine suddenly after using it regularly for a long time, you may have withdrawal. Your doctor may slowly reduce your dose before stopping it. Tell your doctor right away if you notice any symptoms of withdrawal. Withdrawal symptoms can include anxiety, depression, confusion, fever, or muscle stiffness.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting. Do not stand or sit up quickly.

If possible, avoid using with alcohol, marijuana, or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

If you have a painful erection or an erection for more than 4 hours, seek medical care right away.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• dizziness or drowsiness
• dry mouth
• lightheadedness
• irritation of mouth and gum tissue
• nausea and vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• change in behavior
• confusion
• fainting
• hallucinations (unusual thoughts, seeing or hearing things that are not real)
• fast or irregular heart beats
• low blood pressure
• unusual strong urges - such as increased need to shop, gamble, or have sex
• falling asleep suddenly during usual daily activities
• unusual behavior during sleep such as walking, talking, cooking, eating, making phone calls or driving
• unusual or unexplained tiredness or weakness

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.