cosyntropin

What is the most important information I should know about cosyntropin?

Before you receive cosyntropin, tell your doctor about all your medical conditions or allergies, and all the medicines you are using.

What is cosyntropin?

Cosyntropin is a man-made form of a hormone called adrenocorticotropic hormone (ACTH). ACTH is a hormone that is normally produced by the pituitary gland in the brain. ACTH stimulates the adrenal glands to release the hormones cortisol and adrenaline. These hormones help your body respond to stress and also support many systems of the body including circulation, metabolism, immunity, and the nervous system.

Cosyntropin is used as part of a medical test called an ACTH stimulation test. This test can help your doctor diagnose adrenal gland disorders such as Addison's disease, Cushing syndrome, or hypopituitarism (failure of the pituitary gland to produce hormones correctly).

Cosyntropin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving cosyntropin?

Tell your doctor if you have ever had:

• an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or
• an allergic reaction during any prior ACTH stimulation test.

How is cosyntropin given?

Cosyntropin is given as an infusion into a vein. A healthcare provider will give you this injection.

Before you receive cosyntropin, your blood will be drawn to measure your "baseline" level of certain hormones.

Your blood will be drawn again 30 to 60 minutes after cosyntropin was injected, to measure your hormone levels and compare them to the baseline levels. This will help your doctor determine if your pituitary and adrenal functions are normal.

You may need additional medical tests to help your doctor diagnose your condition and determine how best to treat it.

What happens if I miss a dose?

Because you will receive cosyntropin in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving cosyntropin?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of cosyntropin?

Common side effects may include:

• an allergic reaction;
• fast or slow heartbeats;
• increased blood pressure;
• rash; or
• swelling in your hands or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect cosyntropin?

Tell your doctor about all your current medicines, especially a diuretic or "water pill."

Other drugs may affect cosyntropin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about cosyntropin.