Elranatamab Injection (ELRANATAMAB - INJECTION)

Instructions

This medicine is given as an injection.

This medicine should be given by a trained health care provider.

This medicine should only be started in the hospital with proper safety monitoring. Tell doctor right away if medicine is stopped for any reason. You may need to be monitored by a health care professional when restarting this medicine.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Your doctor may prescribe other medications to reduce side effects. Follow instructions carefully.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine is associated with a rare but very serious medical condition. Please speak with your doctor about symptoms you should look out for while on this medicine. Notify your doctor immediately if you develop those symptoms.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive, operate machinery, or do anything else that requires alertness for 48 hours after you take each of the first three doses of this medicine. After 48 hours, only do these activities if you can do them safely. For all other doses, do not drive, operate machinery, or do anything that requires alertness unless you are able to do so safely.

Please check with your doctor before drinking alcohol while on this medicine.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Do not breastfeed while on this medicine. You may safely start breastfeeding 4 months after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women of childbearing age should have a negative pregnancy test before starting this medicine.

Women must use reliable forms of birth control while using this medicine and for 4 months after stopping to prevent pregnancy.

Always carry an ID card or wear a medical alert bracelet indicating your medical condition.

Carry your patient wallet card with you at all times during treatment with this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• decreased appetite
• diarrhea
• lack of energy and tiredness
• pain, redness, swelling near injection
• joint or muscle pain
• nausea

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• bleeding or bruising
• confusion
• coughing
• dizziness or drowsiness
• fever or chills
• headaches
• lightheadedness
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• rapid heartbeat
• shakiness
• skin tingling, burning or prickly feeling
• sore throat
• difficulty speaking

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.