Emtricitabine/Rilpivirine/Tenofovir Disoproxil Oral Tablet (EMTRICITABINE/RILPIVIRINE/TENOFOVIR - ORAL)

Instructions

Keep the medicine in its original container.

Take the medicine with a meal.

Ask your doctor if any of your medicines need to be taken at the same time.

This medicine will work best if you take it at about the same time every day.

Keep the medicine at room temperature. Avoid heat and direct light.

This medicine does not stop the spread of viruses that are passed through the blood or during sex.

Always use condoms during sex.

Do not share needles or other personal objects such as shavers or toothbrushes.

Do not take this medicine with antacids.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is less than 12 hours to the next dose, do not take the dose. Return to your normal dosing schedule. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Use effective birth control to avoid pregnancy.

It is very important that you follow your doctor's instructions for all blood tests.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine may affect areas where fat is stored in the body. This may change your body shape.

Do not use the medication any more than instructed.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Contact your doctor if you notice a change in the amount or darkening of your urine.

Contact your doctor if you develop any signs of a new infection such as fever, cough, sore throat, or chills.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Always refill this medicine before it runs out.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• agitated feeling or trouble sleeping
• decreased appetite
• increased risk for bone fractures
• depression or feeling sad
• diarrhea
• dizziness
• bad dreams
• changes in areas of body fat may alter your body shape
• lack of energy and tiredness
• headaches
• mood changes
• nausea and vomiting
• darkening of skin, especially hands, feet and mouth
• stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• loss of balance
• change in behavior
• bone pain
• unusual bruising or discoloration on skin
• confusion
• swelling of the legs, feet, and hands
• feeling cold or numb, especially in arms and legs
• fever or chills
• numbness or tingling in hands and feet
• signs of kidney damage (such as change in urine color or bubbly urine)
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• muscle pain
• muscle trembling or weakness
• pale or blue skin, lips or fingernails
• shortness of breath
• red, peeling or blistering skin
• light colored stool
• suicidal thoughts
• difficulty swallowing
• swelling in the neck or throat
• unsteadiness while walking
• severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.