Semaglutide Auto-Injector 2 mg/mL (0.5 mL)

Instructions

This medicine is used by injecting it into the skin. Please ask your doctor, nurse or pharmacist for the correct places on your body where this medicine can be injected.

Read and make sure you understand the instructions for measuring dose and using syringe. If you have any questions, talk to your doctor, nurse, or pharmacist.

Always inspect the medicine before using.

The liquid should be clear and colorless.

Do not use the medicine if it contains any particles or if it has changed color.

Store new medicine in the refrigerator until you are ready to use it. Do not allow them to freeze.

If the medicine becomes frozen, you will need to throw it away.

This medicine may be stored at room temperature for up to 28 days.

Do not store above 86 degrees F (30 degrees C).

Protect medicine from light.

Never use any medicine that has expired.

Discard any remaining medicine after your dose is given.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

Do not inject into skin that is bruised, tender, red, hard or has scars or stretch marks.

Change the location of the injection each time. Choose a location at least 1 inch from the last injection.

If you forget to use a dose on time, use it as soon as you remember. If it is within 2 days of the next dose, do not use the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Be sure to follow your regular meal plan and exercise as discussed with your doctor.

Tell your doctor if symptoms do not get better or if they get worse.

This medicine may affect your blood sugar levels. If you have diabetes, talk to your doctor before changing the dose of your diabetes medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine may increase the risk of cancer. Ask your doctor about the benefits and risks.

Do not use the medication any more than instructed.

Severe vomiting or diarrhea may cause the body lose too much water. Contact your doctor right away if you notice symptoms of dehydration, such as unusual dry mouth, increased thirst, urinating less often, lack of tears, or pale or wrinkled skin.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not use this medicine if you are pregnant. If you become pregnant, contact your doctor immediately.

Women must use reliable forms of birth control while taking this medicine and for 2 months after stopping to prevent pregnancy.

Ask your pharmacist how to properly throw away used needles or syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• constipation or diarrhea
• lack of energy and tiredness
• nausea and vomiting
• stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• severe or persistent abdominal pain
• depression or feeling sad
• dizziness
• numbness or tingling in hands and feet
• fast or irregular heart beats
• unusual or long-lasting hoarseness
• signs of kidney damage (such as change in urine color or bubbly urine)
• mood changes
• unusual growth or lump on the neck
• shakiness
• shortness of breath
• suicidal thoughts
• difficulty swallowing
• sweating
• persistent or unusual thirst
• blurring or changes of vision
• severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.