Zepbound Auto-Injector 10 mg/mL (0.5 mL) (TIRZEPATIDE (WEIGHT LOSS) - INJECTION)

Instructions

This medicine is injected into the skin. Ask your doctor, nurse, or pharmacist where on your body this medicine can be injected and how to inject it.

Carefully follow the instructions for preparing this medicine before injection.

Always inspect the medicine before using.

The liquid should be clear or light yellow.

Do not use the medicine if it contains any particles or if it has changed color.

Store at room temperature or in refrigerator. Do not freeze. Protect from light.

Keep the medicine in its original container.

If needed, this medicine may be stored at room temperature for 21 days or fewer.

Never use any medicine that has expired.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

Clean the injection site with alcohol before applying the injector.

You should hear 2 clicks when you inject the medicine. This is normal.

Do not inject into moles, scars, stretch marks, or into skin that is tender, bruised, red, scaly, thickened, or hard.

Change the location of the injection each time. Choose a location at least 1 inch from the last injection.

If you forget to use a dose on time, use it as soon as you remember. If it has been more than 4 days, skip the missed dose and use your next dose as scheduled. Do not use 2 doses of this medicine at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Be sure to follow your regular meal plan and exercise as discussed with your doctor.

This medicine may affect your blood sugar levels. If you have diabetes, talk to your doctor before changing the dose of your diabetes medicine.

This medicine can make birth control pills work less well. Ask your doctor or pharmacist how long you should use an extra form of birth control, such as condoms.

Keep all appointments for medical exams and tests while on this medicine.

Do not use more than 1 dose each week.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine may increase the risk of cancer. Ask your doctor about the benefits and risks.

Do not use the medication any more than instructed.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not use this medicine if you are pregnant. If you become pregnant, contact your doctor immediately.

Ask your pharmacist how to properly throw away used needles or syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• constipation or diarrhea
• lack of energy and tiredness
• pain, redness, swelling near injection
• nausea and vomiting
• stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• severe or persistent abdominal pain
• depression or feeling sad
• dizziness
• dry mouth
• unusual or long-lasting hoarseness
• low blood sugar
• signs of kidney damage (such as change in urine color or bubbly urine)
• lightheadedness
• unusual growth or lump on the neck
• rapid heartbeat
• shakiness
• shortness of breath
• suicidal thoughts
• difficulty swallowing
• excessive or unusual sweating
• persistent or unusual thirst
• blurring or changes of vision
• severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.